The Great Battle against GW1516

Much has been said about the drug GW1516. It had been judged, debated over, talked about and prohibited. Many researches have already studied its benefits and side effects, its mode of action, and its chemical properties. A lot of controversies have come up and caused its prohibition. A lot of athletes have already been suspended from their respective sports due to consumption of the controversial gw1516. So, after all this fuss, where is it now?

gw1516The World Anti-Doping Agency or WADA has already included GW1516 in its prohibited list in 2009 due to its adverse effects. But why were there athletes who still tested positive early last year for GW1516? The questions as to where these people get this drug and how they get it are still hanging in the air leaving WADA and other anti-doping agencies asking themselves as to what could have gone wrong in their anti-doping campaigns.

Despite warnings and alerts released by WADA and health agencies in different countries, a lot of people still use this prohibited drug. Recently, a Russian cyclist had been provisionally suspended after having been tested positive for GW1516. He had been out of his team after a urine sample collected in March 2013 tested positive for the sulfone compound of the drug. The promise of being a cycling champion has been lost and the career that could have led him to his dreams is now gone. Though these athletes may have various reasons for taking this drug- whether for health or performance reasons, WADA has been strict about its anti-doping move to totally ban this drug and suspend athletes who would cross the line.

The same fate awaits the other athletes who are using it. This event is absolutely a clear evidence thatGW1516poses threats not only to your health but also to your goals. But the good thing here is that the several teams involved didn’t tolerate this offense. They adhere to WADA rules and promote clean cycling which the other teams can look up to.

This occurrence has significantly increased awareness among athletes, anti-doping agencies and the masses about this drug. Now, both of its beneficial and adverse effects are known. Two of it’s widely- known adverse effects are cardiovascular problems and malignancies. Due to this drug’s effect on a receptor called PPAR, the body’s metabolism has been greatly altered. Stimulation of PPAR leads to development of type 1 muscles, which are mainly used for endurance exercises. These muscles preferentially make use of your fats, instead of glucose, which could lead to the production of harmful metabolites, such as ketone bodies and lactic acid.

The effects of this drug can even more be augmented by AICAR, chemically known as amin-ribofuranosyl-imidazole-carboxamideribonucleotide. AICAR is an endogenous substrate of nucleic acid synthesis. However, when exogenously administered, it may produce unintended effects in the body. Just like GW1516, it isalso banned by WADA. AICAR also enhances one’s performance by facilitating the uptake of glucose by muscle cells, a phenomenon that leads to increased energy production.However, it has been shown that this drug can promote the production of acidic metabolites in the body, such as lactic acid, that may have dangerous metabolic effects.

Although the development of GW1516 has long been abandoned by GlaxoSmithKline (GSK), its popularity didn’t die down. The controversies that followed must have been the culprit as to its fame. WADA and the cycling governing body, UCI, have made their stand regarding these two substances. They have clearly stated that they will not ever toleratetheir use. GSK has also stopped its development because of possibilities of great health risks. Though they know it will sell millions, they opted not to risk people’s lives.

The big decision here lies on the hands of the consumers. May the people, especially the athletes, who are still using it, be enlightened and take a great step towards good health. Like WADA and UCI, the world is looking forward to a doping-free sport environment!

Investing in Fireproof Safes

Fireproof safes are a great item to have whether it is for your home or office use. There are different types and models that are out in the market. If you are planning to buy one, the first thing you need to do is make a checklist of items you will keep in it. Take note of how valuable and how vulnerable each item is when subjected to heat and fire. This will help you decide on the type and size of the fireproof safe you need. You can ask yourself these questions to help you out:

  • Are you using the safe to store up back-up media?
  • How many items are you storing up?
  • How large are these items?

You can add up more questions that can help you determine the vulnerability of your valuables.

What is a fireproof safe?

Fireproof safes are fireproof safesdesigned to protect its contents for a specific amount of time. It is rated by Underwriters Laboratories according to the time it can protect its contents when subjected to a certain temperature.

The safe may be called “fireproof safe” but it doesn’t mean that it is completely indestructible. Underwriters Laboratories provides rates that can help buyers know how long their valuables are kept safe. If you are looking for a safe, the UL ratings will guarantee you of its quality. Here are UL’s fireproof safe rates.

  • 30 minutes – UL class 350 – It can protect valuables for 30 minutes with an outside temperature of 1550 degrees.
  • 60 minutes – UL class 350 – it can protect valuables for 760 minutes with an outside temperature of 1700 degrees.
  • 1 hour plus – UL class 350 – it can protect valuables for more than one hour with an outside temperature of 1700 degrees. It has also survived an impact from a 30 feet drop.
  • 2 hours – UL class 350 – it can protect valuables for 2 hours with an outside temperature of 1850 degrees.
  • 2 hours plus – UL class 350 – it can protect valuables for more than 2 hours with an outside temperature of 1850 degrees. It has also survived an impact from a 30 feet drop.

Shopping for a safe

The UL ratings can help you select the best safe for you. Once you have identified what safe rate you should go for, the next step is to find a trusted manufacturer. You can search for it online. Read reviews about each brand name and the various sizes of safes they offer.

Consider the safe’s lock too. The locking mechanism can be a combination lock, electronic locks, or biometrics. Select the one which fits your needs for security.

Fireproof safes also come with shelves and compartments. These are made for specific items such as jewelries or documents. Guns also have their own fireproof safe models to choose from. These types of shelves keep items more organized.

The style of your fireproof safe can also help in hiding it further from public sight. One of the best ways to keep your items secure is to also hide the safe well. You can opt for one that can be mounted on the wall or one that can be bolted on the floor. A safe can come in many styles that make it unnoticeable.

Safes are primarily used to protect valuables from burglars. Burglar resistant safes are also a good option. You can have a safe both fireproof and burglar resistant. While this type can be very expensive, it guarantees safety from fire and burglar tampering. It can’t be easily opened.

You should also consider a safe that can protect your items from water, dust, and other elements that can damage your valuables. If a fire occurs, you safe should be able to protect your items from gushing water from the firemen’s hoses.

Fireproof safes are a great investment. Whether it’s for home use or for business, you need to find one that guarantees protection for your personal items or business documents. Determine which items need to be kept in the safe. This will help you find the right safe rating for you.

Author Bio:

Vault And Safe is the #1 source for high quality safes and vaults to protect your valuables. Free Shipping on all safes including home safes, gun safes, drop safes, depository safes, combination safes, TL-15 safes security & fireproof safe to home or office nationwide.

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